CAS & Cleveland Clinic Partner to Accelerate Research in Brain Health & Healthy Aging

The partnership will harness emerging technologies, including artificial intelligence (AI) and quantum computing, to build disease-specific models, starting with Alzheimer's.

CAS, a division of the American Chemical Society focused on scientific content and knowledge management, has announced a strategic collaboration with the Cleveland Clinic, a globally recognized academic health system.

The partnership aims to combine the organizations' technological strengths, clinical expertise, and data capabilities to drive research in healthcare, with an initial focus on brain health and healthy aging.

The announcement was made during the Cleveland Discovery & Innovation Forum, an event that showcases advancements in healthcare and life sciences.

The collaboration seeks to bridge the gap between scientific discovery and clinical application, targeting complex diseases such as Alzheimer's, which currently lacks effective disease-modifying treatments.

Initial Focus: Drug Discovery for Brain Health

The first phase of the partnership will concentrate on drug discovery initiatives for brain health, particularly Alzheimer's disease.

The effort will combine Cleveland Clinic's clinical and biomedical research expertise with CAS's deep scientific data repository through the CAS Content Collection™—one of the world's most comprehensive curated scientific resources.

"This unique collaboration leverages Cleveland Clinic's biomedical research and clinical care with CAS's leadership in scientific data and technology," said Dr. Lara Jehi, Chief Research Information Officer at Cleveland Clinic.

"By combining our strengths, we aim to generate high-quality medical data, validate scientific models, and integrate research into patient care to improve chronic disease management."

Advanced Technologies to Power Discovery

The partnership will harness emerging technologies, including artificial intelligence (AI) and quantum computing, to build disease-specific models, starting with Alzheimer's.

Cleveland Clinic's partnership with IBM provides access to the IBM Quantum System One—the world's first quantum computer dedicated exclusively to healthcare research—enhancing the collaboration's technological foundation.

CAS President Manuel Guzman emphasized the need to reduce the 17-year average lag from lab discovery to approved therapy.

"Our goal is to close that gap through scientific innovation. By combining high-quality content, advanced technologies, and deep subject matter expertise, we aim to deliver meaningful outcomes for patients and society."

The initiative also aligns with the Cleveland Innovation District's goals to foster job creation, accelerate research, and build a skilled workforce.

Supported by the State of Ohio and JobsOhio, the district unites healthcare and academic institutions to advance research-driven growth.

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